Matrix assisted laser desorption ionisation mass spectrometry imaging (MALDI-MSI)
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United States of America Patent
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Feb 16, 2016
Grant Date -
Mar 27, 2014
app pub date -
Mar 1, 2012
filing date -
Mar 9, 2011
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Abstract
A method of preparing a sample for matrix assisted laser desorption ionization mass spectrometry imaging analysis by a two-step process. Firstly, a MALDI matrix is dusted on to the sample followed by a spray of a suitable solvent onto the dusted sample. The present method has been successfully applied to the detection and mapping of several analyte classes in latent fingermarks. Using the present two-step method, fingermark enhancement, recovery and analysis from different substrate surfaces is now possible enabling visual and chemical information to be obtained simultaneously via remote testing.
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