Yeast production host cells
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United States of America Patent
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Feb 16, 2016
Grant Date -
May 26, 2011
app pub date -
Sep 29, 2010
filing date -
Sep 29, 2009
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Abstract
Crabtree positive yeast cells that have endogenous expressed pyruvate decarboxylase genes inactivated and an engineered biosynthetic pathway utilizing pyruvate were found to have improved growth and product yield when glucose repression was reduced. These cells were able to grow in media containing a high glucose concentration.
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