Peptide sequence design and use thereof for peptide-mediated siRNA delivery
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United States of America Patent
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Feb 16, 2016
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Nov 23, 2012
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Nov 24, 2011
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Abstract
The invention provides, in one aspect, peptides and a complex comprising one of the peptides and a cargo molecule, wherein the peptide and the cargo molecule are coupled by non-covalently. The peptides of the invention were found to facilitate the delivery of siRNA molecules into cells and to function in siRNA mediated silencing of cellular targets.
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