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United States of America Patent

PATENT NO 9259461
APP PUB NO 20110189215A1
SERIAL NO

13062319

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to immunogenic compositions comprising neisserial blebs with upregulated levels of the NMB0964 antigens such that bacterial antibodies are generated against said antigen. Methods are also provided to upregulate expression through removal of the zinc repression mechanism of the cell or promoter or through removal of zinc from the culture medium.

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Patent Owner(s)

Patent OwnerAddress
GLAXOSMTHKLINE BIOLOGICALS S ARUE DE L'INSTITUT 89 RIXENSART B-1330

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bos, Martine Petronella Utrecht, NL 5 58
Poolman, Jan Rixensart, BE 118 1219
Stork, Michiel Utrecht, NL 6 11
Tommassen, Johannes Petrus Maria Utrecht, NL 16 79
Weynants, Vincent Rixensart, BE 30 137

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