Benzothiazole-based pyridinium compounds
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United States of America Patent
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Feb 9, 2016
Grant Date -
Sep 17, 2015
app pub date -
Aug 23, 2012
filing date -
Aug 23, 2011
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Abstract
The compositions of the invention are novel benzothiazol-based pyridinium compounds with potent acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities. Such compositions can be used, for example, to treat Alzheimer's Disease and other neurodegenerative disorders. The compounds of the invention can also be used to prevent or treat the neurotoxic effects of nerve agents (e.g., sarin gas or insecticides).
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