Long-acting coagulation factors and methods of producing same
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United States of America Patent
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Feb 2, 2016
Grant Date -
Nov 7, 2013
app pub date -
Jul 1, 2013
filing date -
Feb 3, 2006
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Abstract
Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using and producing same are also disclosed.
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