Composition and formulation comprising recombinant human iduronate-2-sulfatase and preparation method thereof
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United States of America Patent
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Feb 2, 2016
Grant Date -
Nov 12, 2015
app pub date -
Jul 27, 2015
filing date -
Jun 24, 2011
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Abstract
Disclosed are a composition comprising recombinant iduronate-2-sulfatase (IDS) and a method for treating Hunter syndrome. The glycosylation pattern and formylglycine content of the IDS composition are different from those of ELAPRASE® and have superior pharmaceutical efficacy and are safer than the conventional agent and thus can be effectively used for the therapy of Hunter syndrome.
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