Alpha-fetoprotein “ring and tail” peptides

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United States of America Patent

PATENT NO 9249189
APP PUB NO 20130059794A1
SERIAL NO

13522882

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Abstract

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The invention relates to compounds that are analogs of a cyclic peptide, cyclo[EKTOVNOGN] (SEQ ID NO: 13), AFPep, that has anti-estrotrophic activity. The analogs of the invention include peptides and peptidomimetics that inhibit estrogen receptor-dependent cell proliferation. The compounds of the invention are useful for treating cell proliferative disorders or physiological conditions characterized by undesirable or unwanted estrogen induced cell proliferation, including breast cancer.

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Patent Owner(s)

Patent OwnerAddress
ALBANY MEDICAL COLLEGE47 NEW SCOTLAND AVENUE ALBANY NY 12208

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andersen, Thomas T Albany, US 13 86
Bennett, James A Delmar, US 25 246
Bryan, Alberto Philadelphia, US 2 2
Jacobson, Herbert I Albany, US 9 48
Joseph, Leroy Albany, US 3 8

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