C-3 alkyl and alkenyl modified betulinic acid derivatives
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United States of America Patent
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Feb 2, 2016
Grant Date -
Aug 28, 2014
app pub date -
Feb 21, 2014
filing date -
Feb 25, 2013
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Abstract
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, alkyl and alkenyl C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II, III and IV:
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