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Abstract

An anti-human-norovirus GII antibody which responds to substantially all genotypes of the human noroviruses belonging to GII and which can comprehensively detect such human noroviruses GII. The anti-human-norovirus GII antibody that binds to at least one of epitopes which are contained in amino acid regions represented by the following formulas (1) and (2):

description='In-line Formulae' end='lead'P-X¹-X²-P-G-E  (1) (SEQ ID NO: 2)description='In-line Formulae' end='tail'

description='In-line Formulae' end='lead'X³-X⁴-X⁵-F-Y-X⁶-L-X⁷-P-X⁸  (2) (SEQ ID NO: 3)description='In-line Formulae' end='tail'

(wherein, X¹ represents L, V, N, T, S, M, or R; X² represents F, Y, or M; X³ represents V or G; X⁴ represents N or S; X⁵ represents Q, P, or S; X⁶ represents S, T, or I; X⁷ represents A or S; and X⁸ represents M or V), and of an epitope formed of amino acid 483 of the amino acid sequence represented by SEQ ID NO: 1, or an epitope formed of an amino acid corresponding to amino acid 483, the regions and the amino acids being present in the P domain of a capsid structural protein of a human norovirus GII.

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