Combination therapy with MDM2 and EFGR inhibitors

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United States of America Patent

PATENT NO 9238641
APP PUB NO 20150105412A1
SERIAL NO

14571770

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Abstract

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Provided is a method of treating a proliferative disease, condition, or disorder in a subject by administering a combination of an inhibitor of p53 and MDM2 binding and an EGFR inhibitor. Various embodiments of the disclosed methods provide a synergistic anti-proliferative or anti-apoptotic effect compared to administration of one agent alone.

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Patent Owner(s)

  • ERRICO, JOSEPH P.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allocco, John Staten Island, US 7 78
Bastos, Margarita Plainsboro, US 14 93
Errico, Joseph P Warren, US 394 31506
Mugrage, Benjamin Cranbury, US 13 151
Ong, Jane Franklin Park, US 12 108
Sills, Matthew Berkeley Heights, US 21 154
Turchi, Ignatius Yardley, US 7 78
Wines, Pam Manalapan, US 7 78

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