Enzymatical modification of cell glycosylation using serum albumin and divalent cations
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United States of America Patent
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Jan 12, 2016
Grant Date -
Jun 9, 2011
app pub date -
Jul 16, 2009
filing date -
Jul 16, 2008
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Abstract
The invention is directed to a method and kit to control and modify the status of cells, such as human stem cells, by changing their glycosylation, in particular sialylation and fucosylation, levels in a reaction condition where culture medium reagents, such as divalent cations, are present and cells are kept non-adherent. The invention is further directed to novel stem cells, the glycosylation of which has been specifically altered.
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