Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof
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United States of America Patent
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Jan 12, 2016
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Oct 8, 2014
filing date -
Apr 20, 2012
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Abstract
The present disclosure provides hetero-bicyclic compounds of formula (I), their tautomers, polymorphs, stereoisomers, prodrugs, solvates, hydrates, N-oxides, co-crystals, pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of treating conditions and diseases that are mediated by Bruton's tyrosine kinase (Btk) activity, The disclosure also relates to the process of preparation of compounds of Formula (I).
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