Dopamine D3 receptor ligands and preparation and medical uses of the same
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United States of America Patent
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Jan 5, 2016
Grant Date -
Nov 6, 2014
app pub date -
Jun 3, 2014
filing date -
Oct 10, 2008
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Abstract
The present invention relates to a novel piperazine derivative represented by Formula I having an activity for regulating dopamine D3 receptor, stereoisomers thereof, pharmaceutically acceptable salts or solvates, and a pharmaceutical composition comprising the compound, a process for preparing the same, and use thereof in the prevention or treatment of a disease associated with central nervous system dysfunction, such as Parkinson's disease, schizophrenia, drug addiction and relapse, as well as kidney protection and immunoregulation, or as a tool for researching D3R function or diseases associated with D3R dysfunction.
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