Uridine di- or tri-phosphate derivatives and uses thereof
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United States of America Patent
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Dec 29, 2015
Grant Date -
Dec 5, 2013
app pub date -
Dec 1, 2011
filing date -
Dec 1, 2010
priority date (Note) -
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Abstract
The disclosure provides particular uridine di- and tri-phosphate compounds of Formula I, and pharmaceutical compositions thereof. The definitions of variables such as R, Y, B, m, Z1, Z2, and Z3 are as provided in the disclosure. These compounds are useful for treatment of diseases, disorders and conditions modulated by P2Y6 receptors, and particularly for lowering intraocular pressure and thereby treating ocular hypertension and/or glaucoma.
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