Methods of reducing symptoms in subjects using single dosage forms with tapering release rates
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United States of America Patent
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Dec 29, 2015
Grant Date -
Nov 10, 2011
app pub date -
May 5, 2011
filing date -
May 5, 2010
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Abstract
The present invention is directed to methods of reducing symptoms associated with an abrupt reduction in an endogenous or exogenous chemical in subjects, the methods comprising: (a) administering to the subject a single dosage form comprising an active agent, wherein the release rate of the active agent from the single dosage form tapers throughout the administration; and (b) removing the single dosage form from the subjects after the release rate of the active agent is at or below a terminal symptom threshold level.
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