Use of YSCF, truncated YSCF and YSCF homologs as adjuvants

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United States of America Patent

PATENT NO 9211327
SERIAL NO

14126405

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Abstract

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An antigenic composition comprising an antigen and an effective adjuvant, the adjuvant comprising isolated or recombinant YscF, a YscF fragment, truncated YscF (trYscF), or homologs thereof. A method of inducing an enhanced immune response comprising administering an antigen and an effective adjuvant comprising isolated or recombinant YscF, a YscF fragment, trYscF, or homologs thereof. An antigenic composition produced by a process comprising providing a host cell with an expression vector containing a nucleotide sequence encoding YscF, a YscF fragment, trYscF, or YscF homolog capable of acting as an adjuvant; expressing the nucleotide sequence in the host cell to produce the protein; and mixing the collected protein with a suitable excipient.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF NORTH DAKOTA264 CENTENNIAL DRIVE TWAMLEY HALL ROOM 105A GRAND FORKS ND 58202

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nilles, Matthew Grand Forks, US 1 1

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