Method of deleting an IgM gene in an isolated rat cell
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United States of America Patent
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Dec 8, 2015
Grant Date -
Aug 26, 2010
app pub date -
Dec 3, 2009
filing date -
Dec 4, 2008
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Abstract
Disclosed herein are methods and compositions for genome editing of one or more loci in a rat, using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
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