Monoclonal antibodies and method of immunological analysis of D-dimer
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United States of America Patent
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Dec 8, 2015
Grant Date -
Jan 10, 2013
app pub date -
Mar 31, 2011
filing date -
Apr 1, 2010
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Abstract
Provided are an antibody capable of specifically and accurately measuring digested products of stabilized fibrin (D-dimer), and a method and a reagent for measuring D-dimer using the antibody. The antibody specifically reacts with D-dimer, which is plasmin-digested products of stabilized fibrin, but does not react with fibrinogen or plasmin-digested products of fibrinogen, which include fragment X, fragment Y, fragment D1, and fragment E3, and does not react with dissociation products of DD/E monomer, which include fragment DD, fragment E1, and fragment E2.
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