Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF)

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United States of America Patent

PATENT NO 9206125
APP PUB NO 20130203738A1
SERIAL NO

13578230

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Abstract

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The present invention identifies a compound which binds to the PAH1 domain of mSin3B that specifically binds to neural restrictive silencer factor NRSF, and uses the compound as a prophylactic and/or a therapeutic for diseases associated with abnormal expression of neural restrictive silencer factor NRSF/REST or abnormal expression of genes targeted by NRSF/REST, such as Huntington's disease, medulloblastoma and neuropathic pain.

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Patent Owner(s)

Patent OwnerAddress
PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY22-2 SETO KANAZAWA-KU YOKOHAMA-SHI KANAGAWA 2360027
NAGASAKI UNIVERSITYNAGASAKI 852-8521
NAGOYA CITY UNIVERSITY1 AZA KAWASUMI MIZUHO-CHO MIZUHO-KU NAGOYA-SHI AICHI 467-8601

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goshima, Yoshio Yokohama, JP 6 18
Hiraishi, Ryuta Nagoya, JP 1 6
Hirao, Yuuka Yokohama, JP 1 6
Miyata, Naoki Nagoya, JP 13 64
Nagadoi, Aritaka Yokohama, JP 1 6
Nishimura, Yoshifumi Yokohama, JP 25 226
Suzuki, Takayoshi Nagoya, JP 105 921
Ueda, Hiroshi Nagasaki, JP 546 6423
Yamashita, Naoya Yokohama, JP 18 155

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