Tunable sustained release of a sparingly soluble hydrophobic therapeutic agent from a hydrogel matrix
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United States of America Patent
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Dec 8, 2015
Grant Date -
Nov 18, 2010
app pub date -
May 21, 2010
filing date -
Apr 25, 2005
priority date (Note) -
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Abstract
The incorporation of polymeric excipients into an injectable hydrogel matrix, for example, methyl cellulose in the case of a hydrogel matrix comprising hyaluronan and methylcellulose (HAMC) has been found to increase the solubility of sparingly soluble hydrophobic drugs and tune their rate of release. The hydrogel matrix may also include other sparingly soluble hydrophobic food or cosmetic agents.
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