Human binding molecules capable of binding to and neutralizing influenza B viruses and uses thereof
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United States of America Patent
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Dec 1, 2015
Grant Date -
Feb 5, 2015
app pub date -
Oct 13, 2014
filing date -
Mar 8, 2012
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Abstract
Described are binding molecules, such as human monoclonal antibodies, that bind to hemagglutinin of influenza B viruses, and have a broad neutralizing activity against such influenza viruses. These binding molecules do not bind to hemagglutinin of influenza A viruses. Further provided are nucleic acid molecules encoding the binding molecules, and compositions comprising the binding molecules. The binding molecules can be used in the diagnosis of, prophylaxis against, and/or treatment of influenza B virus infections.
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