T cell receptors specific for immunodominant CTL epitopes of HCV
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United States of America Patent
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Nov 24, 2015
Grant Date -
Jan 10, 2013
app pub date -
Nov 23, 2010
filing date -
Nov 24, 2009
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Abstract
The present invention relates generally to the field of immunology. More particularly, aspects of the invention concern the discovery of several T cell receptors (TCRs) that are specific for an immunodominant CTL epitope of hepatitis C virus (HCV). Embodiments include TCRs, DNAs encoding TCRs, methods of making TCRs, and methods of using TCRs to treat, prevent or inhibit hepatitis C virus (HCV) proliferation.
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