Conformationally-preorganized, miniPEG-containing γ-peptide nucleic acids
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United States of America Patent
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Nov 24, 2015
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May 8, 2014
app pub date -
Apr 6, 2012
filing date -
Apr 8, 2011
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Abstract
The present invention relates to γ-PNA monomers according to Formula I where substituent groups R1, R2, R3, R4, R5, R6, B and P are defined as set forth in the specification. The invention also provides methodology for synthesizing compounds according to Formula I and methodology for synthesizing PNA oligomers that incorporate one or more Formula I monomers.
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