EphA4 is a disease modifier in motor neuron disease
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United States of America Patent
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Nov 17, 2015
Grant Date -
May 22, 2014
app pub date -
May 14, 2012
filing date -
May 13, 2011
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Abstract
The present application relates to the field of motor neuron diseases, most particularly to amyotrophic lateral sclerosis and spinomuscular atrophy. Provided herein are strategies to improve symptoms and increase survival in patients with these axonopathies by inhibiting signaling mediated by the EphA4 ephrin receptor.
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