Methods for producing methionine by culturing a microorganism modified to enhance production of cysteine
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United States of America Patent
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Nov 17, 2015
Grant Date -
Jul 18, 2013
app pub date -
Jan 9, 2013
filing date -
Jan 4, 2006
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Abstract
A method of producing methionine, derivatives or precursors thereof includes culturing a modified microorganism in a culture medium comprising a source of carbon and a source of sulfur; and recovering methionine from the culture medium, wherein said modified microorganism has an increased expression of cysE gene encoding serine acetyltransferase, metH gene encoding methionine synthase and metF gene encoding 5,10-methylenetetrahydrofolate reductase compared to expression of the cysE, metH and metF genes in an unmodified microorganism.
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