Polypeptide derived from protein A and able to bind PDGF
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United States of America Patent
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Nov 17, 2015
Grant Date -
Jan 27, 2011
app pub date -
Dec 17, 2008
filing date -
Dec 19, 2007
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Abstract
The invention provides a platelet derived growth factor receptor beta (PDGF-Rβ) binding polypeptide, comprising a platelet derived growth factor receptor beta binding motif, PBM, which motif consists of an amino acid sequence as defined herein, wherein the PDGF-Rβ-binding polypeptide binds to PDGF-Rβ such that the KD value of the interaction is at most 1×10−6 M. Also provided are methods and uses of said polypeptide in treatment and diagnosis of PDGF-Rβ-related conditions.
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