Drug-eluting catheter and method of manufacturing the same
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United States of America Patent
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Nov 17, 2015
Grant Date -
Jan 27, 2011
app pub date -
Mar 12, 2009
filing date -
Mar 12, 2008
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Abstract
Biocompatible nanoparticles 1 which entrap a bioactive substance and whose surface is positive-charge-modified are electrically adhered to a balloon portion 9 of a catheter main body 5 through a negatively charged resin layer 11, and thus a nanoparticle layer 12 is formed. After the catheter main body 5 is indwell in vivo, the nanoparticles 1 are gradually eluted from the nanoparticle layer 12 and are effectively delivered to cells.
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