Establishment of rhesus monkey model of autoimmunity type 1 diabetes

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United States of America Patent

PATENT NO 9186421
APP PUB NO 20130149733A1
SERIAL NO

13637125

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Abstract

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Use of low dose streptozocin in the preparation of an animal model for screening drugs for treatment of antoimmune type 1 diabetes is disclosed, in which streptozocin is administrated intravenously at a dose of 15-30 mg/kg per time for 5 days and administrated again on the 7th day and 14th day after last time of offering drug. A method for preparing rhesus monkey model of autoimmune type 1 diabetes and autoimmune type 1 diabetes animal model obtained are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
WEST CHINA HOSPITAL SICHUAN UNIVERSITYNO 37 GUOXUEXIANG WUHOU DISTRICT CHENGDU SICHUAN 610041

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Younan Chengdu, CN 1 0
Cheng, Jingqiu Chengdu, CN 4 0
Deng, Shaoping Chengdu, CN 1 0
He, Sirong Chengdu, CN 1 0
Jin, Xi Chengdu, CN 7 2
Li, Hongxia Chengdu, CN 24 74
Lu, Yanrong Chengdu, CN 2 0
Mai, Gang Chengdu, CN 1 0
Qiao, Chaofeng Chengdu, CN 1 0
Ren, Yan Chengdu, CN 108 196
Tian, Bole Chengdu, CN 1 0
Wang, Li Chengdu, CN 972 6677
Wei, Lingling Chengdu, CN 1 0
Zeng, Li Chengdu, CN 82 534
Zhang, Wensheng Chengdu, CN 29 43

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