C.difficile toxin B CROP domain peptides, antibodies and complexes thereof

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United States of America Patent

PATENT NO 9181632
SERIAL NO

14479735

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Abstract

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The present invention provides polypeptide domains of C. difficile toxin B (B1, B2, B3, B4) and complexes between the polypeptides and antibodies that bind specifically for the polypeptide. Methods of using the polypeptides to generate antibodies are also provided.

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME LLC126 EAST LINCOLN AVENUE RAHWAY NJ 07065

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hernandez, Lorraine Warren, US 1 6
Murgolo, Nicholas Millington, US 3 121
Orth, Peter Bronxville, US 39 450
Reichert, Paul Montville, US 40 347
Sheth, Payal Somerset, US 1 6
Strickland, Corey Martinsville, US 29 292
Therien, Alex Fanwood, US 1 6
Xiao, Li Cranbury, US 237 1309

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