Method of treatment of breast cancers over-expressing the SHP2 signature genes
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United States of America Patent
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Nov 10, 2015
Grant Date -
May 15, 2014
app pub date -
Jun 5, 2012
filing date -
Jun 6, 2011
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Abstract
A method for treating breast cancer in a subject having a breast cancer over-expressing the “SHP2 signature” genes, as compared to normal breast tissue samples, which method comprises the step of administering to said subject a therapeutically effective amount of a modulator of the protein tyrosine phosphatase, non-receptor type 11 (PTPN11) gene or of its gene product (Shp2).
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