Compositions containing HC-HA complex and methods of use thereof
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United States of America Patent
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Nov 3, 2015
Grant Date -
Apr 5, 2012
app pub date -
Apr 26, 2010
filing date -
Apr 24, 2009
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Abstract
Disclosed herein, in certain embodiments, is an HC•HA complex comprising hyaluronan and a heavy chain of IαI, wherein the transfer of the heavy chain of IαI is catalyzed by TSG-6. Further disclosed herein, in certain embodiments, is an HC•HA complex comprising hyaluronan and a heavy chain of IαI, wherein the transfer of the heavy chain of IαI is catalyzed by the TSG-6 like protein. Additionally, disclosed herein are methods of manufacturing said complex and methods of use thereof.
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