Transition metal complexes of bis[thiohydrazide amide] compounds
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United States of America Patent
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Nov 3, 2015
Grant Date -
Dec 1, 2011
app pub date -
Oct 21, 2009
filing date -
Oct 22, 2008
priority date (Note) -
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Abstract
The present invention is directed to a compound comprising a bis[thiohydrazide amide] or a deprotonated form thereof, complexed to a transition metal cation, wherein the bis[thiohydrazide amide] is represented by Structural Formula (I), or a prodrug, isomer, ester, salt, hydrate, solvate, polymorph or a deprotonated form thereof. In one embodiment, the compound is represented by Structural Formula (II), or a prodrug, isomer, ester, salt, hydrate, solvate or polymorph thereof. The present invention also provides a pharmaceutical composition comprising the compound of the invention and method of use thereof.
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