Prodrugs containing an aromatic amine connected by an amido bond to a linker

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United States of America Patent

PATENT NO 9173953
SERIAL NO

13387981

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Abstract

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The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising a drug linker conjugate D-L, wherein an aromatic amine containing biologically active moiety is connected (bound) by an amido bound to a linker. The invention also relates to pharmaceutical compositions comprising said prodrugs and their use as medicaments.

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ASCENDIS PHARMA A/S2900 HELLERUP

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baron, Julia Heidelberg, DE 3 39
Hersel, Ulrich Fritz-Frey-Strasse, DE 72 1020
Krusch, Mathias Hirschhorn, DE 18 130
Rau, Harald Dossenheim, DE 112 1733

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