Acadesine derivatives, products and compositions including same, therapeutic uses thereof, and methods for synthesizing same
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United States of America Patent
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Nov 3, 2015
Grant Date -
Jun 26, 2014
app pub date -
Apr 17, 2012
filing date -
Apr 18, 2011
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Abstract
Acadesine derivatives as a drug, as well as the derivatives for the treatment of cancer and in particular for the treatment of chronic myeloid leukemia are described. Also, product containing the derivatives and at least one second active ingredient as a combination product for simultaneous, separate or sequential administration, in the treatment of cancer, as well as a pharmaceutical composition containing the derivatives and a pharmaceutically acceptable carrier are described. Finally, a method for inhibiting the in vitro cell proliferation including the placement of an in vitro cell in contact with the derivatives and methods for synthesis of said derivatives and methods for synthesis of the derivatives are described.
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