Isomerases, nucleic acids encoding them and methods for making and using them

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United States of America Patent

PATENT NO 9169478
APP PUB NO 20140141491A1
SERIAL NO

13967157

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Abstract

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This invention relates generally to enzymes, polynucleotides encoding the enzymes having isomerase activity, e.g., racemase activity, e.g., amino acid racemase activity, alanine racemase activity, and/or epimerase activity, and/or catalyze the re-arrangement of atoms within a molecule, catalyze the conversion of one isomer into another, catalyze the conversion of an optically active substrate into a raceme, which is optically inactive, catalyze the interconversion of substrate enantiomers, catalyze the stereochemical inversion around the asymmetric carbon atom in a substrate having only one center of asymmetry, catalyze the stereochemical inversion of the configuration around an asymmetric carbon atom in a substrate having more than one asymmetric center, and/or catalyze the racemization of amino acids.

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Patent Owner(s)

Patent OwnerAddress
BASF ENZYMES LLC3550 JOHN HOPKINS COURT SAN DIEGO CA 92121

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bueno, Analia San Diego, US 12 57
Burke, Ellen G San Diego, US 5 33
Cuenca, Joslin M San Diego, US 6 15
De, Souza Mervyn L Plymouth, US 15 302
Kollmann, Sherry Maple Grove, US 3 3
Luginbuhl, Peter San Diego, US 38 358
Weiner, David P San Diego, US 27 357

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