Methods for preparing 17-alkynyl-7-hydroxy steroids and related compounds-2
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United States of America Patent
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Oct 20, 2015
Grant Date -
Mar 14, 2013
app pub date -
Oct 30, 2012
filing date -
Jun 6, 2008
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Abstract
The invention relates to processes for preparing 17-alkynyl-7-hydroxy-steroids, such as 17-Ethynyl-10R,13S-dimethyl 2,3,4,7,8R,9S,10,11,12,13,14S,15,16,17-hexadecahydro-1H-cyclopenta[a]phenanthrene-3R,7R,17S-triol (also referred to as 17α-ethynyl-androst-5-ene-3β,7β,17β-triol), that are essentially free of process impurities having binding activity at nuclear estrogen receptors.
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