Method and an insertable medical device for delivering one or more pro-healing agents to a target site within a blood vessel post-deployment of a stent
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United States of America Patent
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Oct 20, 2015
Grant Date -
Nov 1, 2012
app pub date -
Jan 17, 2011
filing date -
Jan 25, 2010
priority date (Note) -
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Abstract
The invention discloses an insertable medical device for delivering one or more pro-healing agents to a site of deployment of a stent in a blood vessel. The surface of the insertable medical device is coated with nano-carriers that include the one or more pro-healing agents encapsulated with one or more biological agents. The nano-carriers are released when the insertable medical device is expanded at the site. The nano-carriers thus released penetrate tissues at the site resulting in dissolution of the one or more biological agents. Thereafter, the one or more pro-healing agents are released from the nano-carriers at the site. Thus, an in-tissue release of the one or more pro-healing agents at the site is achieved thereby improving endothealization, extracellular matrix formation and healing at the site post deployment of the stent in the blood vessel.
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