Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide
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United States of America Patent
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Oct 13, 2015
Grant Date -
Dec 19, 2013
app pub date -
Jun 6, 2013
filing date -
Jun 8, 2012
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Abstract
The present invention provides fusion proteins comprising a mucin-domain polypeptide covalently linked to an active protein that has improved properties (e.g. pharmacokinetic and/or physicochemical properties) compared to the same active protein not linked to mucin-domain polypeptide, as well as methods for making and using the fusion proteins of the invention.
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