siRNA targeting VEGFA and methods for treatment in vivo
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United States of America Patent
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Oct 6, 2015
Grant Date -
Jan 30, 2014
app pub date -
Aug 27, 2013
filing date -
Jul 28, 2010
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Abstract
Vascular endothelial growth factor A (VEGFA) is a chemical signal produced by cells that stimulates the growth of new blood vessels, and overexpression of VEGFA can lead to undesirable physiological conditions. Through the identification of new siRNA and modifications that improve the silencing ability of these siRNA in vivo, therapeutic compositions and methods have been invented to address the problems associated with this overexpression.
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