Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles
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United States of America Patent
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Oct 6, 2015
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Oct 9, 2014
app pub date -
Nov 14, 2013
filing date -
Nov 14, 2012
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Abstract
The present invention relates to a skin composition which has an excellent effect on smoothing or repairing wrinkles. The composition comprises Palmitoyl Tripeptide-38 (Palmitoyl-Lysyl-Dioxymethionyl-Lysine) and Piper nigrum (Pepper) seed Extract which combination has been found to result in a synergistic effect on hyaluronan synthase 1 (HAS1) mRNA expression in human fibroblasts. The hyaluronan synthase is responsible for the synthesis of hyaluronan (hyaluronic acid) in skin. Hyaluronic acid is a constituent of the extracellular matrix of the skin and responsible for space filling, tissue repair and retention of moisture.
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