Foot and mouth disease virus with increased stability and its use as vaccine
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United States of America Patent
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Sep 29, 2015
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Sep 5, 2013
app pub date -
Sep 8, 2011
filing date -
Sep 8, 2010
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Abstract
The present invention provides a foot and mouth disease (FMD) virus having improved stability compared to the field isolate of the same subtype, wherein the virus comprises one or more amino acid mutations along a line of symmetry of the capsid structure. The present invention also relates to a vaccine comprising such an FMD virus and its use to prevent foot and mouth disease.
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