Material for screening for compound acting on ion channel and use thereof

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United States of America Patent

PATENT NO 9133496
APP PUB NO 20130183709A1
SERIAL NO

13807464

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Abstract

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An object of the present invention is to provide a screening system that targets ion channels and has superior efficiency. The present invention provides a material for screening for compounds that act on a target ion channel, comprising cells which retain at least one first DNA encoding a voltage-dependent Na ion channel that has been inhibited from being inactivated, and in which a K ion channel has been activated so that a resting membrane potential becomes deeper in a negative direction.

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Patent Owner(s)

Patent OwnerAddress
PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY1 AZA-KAWASUMI MIZUHO-CHO MIZUHO-KU NAGOYA-SHI AICHI 4678601
CHANNELOSEARCH TECHNOLOGY3-1 TANABE-DORI MIZUHO-KU NAGOYA-SHI AICHI 4670027

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujii, Masato Nagoya, JP 54 338
Imaizumi, Yuji Nagoya, JP 8 40
Ohya, Susumu Nagoya, JP 1 2
Yamamura, Hisao Nagoya, JP 2 2

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