Method for production of reprogrammed cell using chromosomally unintegrated virus vector
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United States of America Patent
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Sep 8, 2015
Grant Date -
Nov 24, 2011
app pub date -
Jul 16, 2009
filing date -
Jul 16, 2008
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Abstract
An objective of the present invention is to provide vectors for conveniently and efficiently producing ES-like cells in which foreign genes are not integrated into the chromosome. The present inventors discovered methods for producing ES-like cells from somatic cells using chromosomally non-integrating viral vectors. Since no foreign gene is integrated into the chromosome of the produced ES-like cells, they are advantageous in tests and research, and immunological rejection and ethical problems can be avoided in disease treatments.
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