Methods of treating hemophilia using monoclonal antibodies against activated protein C

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United States of America Patent

PATENT NO 9127072
APP PUB NO 20120164150A1
SERIAL NO

13306301

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Abstract

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The present invention provides monoclonal antibodies that selectively bind to and inhibit activated protein C without binding to or inhibiting unactivated protein C. Other antibodies inhibit both activated protein C and activation of unactivated protein C. Methods of treatment employing these antibodies are described herein as are methods of screening for and detecting these antibodies.

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Patent Owner(s)

  • OKLAHOMA MEDICAL RESEARCH FOUNDATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Esmon, Charles Oklahoma City, US 2 6
Xu, Jun Edmond, US 1004 7793

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