Method for synthesizing rivaroxaban intermediate, 4-(4-[(5S)-(aminomethyl)-2-oxo-1,3-oxazoligdin-3-YL]phenyl)morpholin-3-one

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United States of America Patent

PATENT NO 9126990
SERIAL NO

14126361

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Abstract

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The present invention discloses novel methods for synthesizing Rivaroxaban intermediate, i.e., 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. The novel methods provided in the present invention involve mild reaction conditions, convenient operations, easy purification, and low production costs, and thus the process is environmental-friendly and suitable for industrial production.

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Patent Owner(s)

Patent OwnerAddress
ZHEJIANG HUAHAI PHARMACEUTICAL CO LTD317024 FLOOD BRIDGE LINHAI CITY TAIZHOU CITY ZHEJIANG PROVINCE TAIZHOU CITY ZHEJIANG PROVINCE 317024
SHANGHAI SYNCORES TECHNOLOGIES INC538 CAILUN RD PUDONG SHANGHAI 201203

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Huang, Luning Shanghai, CN 21 11
Zhang, Jeannie Shanghai, CN 2 0
Zi, Chunpeng Shanghai, CN 1 0

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