Impedance spectroscopy-based cellular analysis device
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United States of America Patent
Stats
-
Sep 1, 2015
Issued Date -
N/A
app pub date -
Jul 28, 2008
filing date -
Jul 26, 2007
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
An electrical impedance sensing device which integrates multielectrode automated impedance spectroscopy capability with automatic parameter extraction and data analysis to create an automated cell behavior monitoring system. The device comprises radial electrodes and an out-of-plane counter electrode. Quantitative impedance data provided information on cell adhesion, spreading, proliferation and detachment due to cell cycle processes as well as cell-drug interaction, with spatio-temporal resolution. The resulting dataset is processed for impedance distribution and used to characterize cellular motion, morphology, electrochemical and dielectric properties. Also, a method is described for studying cell-cell and cell-matrix interactions, determining electrical characteristics of cell layers, and identifying specific impedance parameters for cancer screening, drug screening, bacterial growth monitoring, organ transplant compatibility, and cell-drug interaction among other applications.
First Claim
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International Classification(s)
- 2008 Application Filing Year
- C12M Class
- 743 Applications Filed
- 353 Patents Issued To-Date
- 47.52 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 14 Citation Count
- C12M Class
- 78.16 % this patent is cited more than
- 10 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Mar 1, 2027 |