Biologic compounds directed against death receptor 5
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United States of America Patent
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Sep 1, 2015
Grant Date -
Dec 29, 2011
app pub date -
Feb 9, 2011
filing date -
Feb 10, 2010
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Abstract
The present invention relates to amino acid sequences that are directed against TRAIL cell surface receptor 2 (herein also “DR5”), as well as to compounds or constructs thereof, and in particular proteins and polypeptides and nucleotides that encode them (referred to herein in their entirety as “NB agents”) and fragments thereof, and pharmaceutically effective variants thereof, and their use in the diagnosis and treatment of DR5 associated diseases and disorders.
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