Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
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United States of America Patent
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Sep 1, 2015
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Apr 26, 2013
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Apr 27, 2012
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Abstract
The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these anti-EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
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