Process and intermediates for preparing macrolactams
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United States of America Patent
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Sep 1, 2015
Grant Date -
Oct 17, 2013
app pub date -
Dec 13, 2011
filing date -
Dec 14, 2010
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Abstract
The present invention relates to macrolactam compounds, intermediates useful in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing and modifying macrolactams. One use of the compounds and methods described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. An example of an HCV inhibitory compound that can be synthesized using the procedures described herein is Compound A and derivative thereof.
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